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For the vast majority of people Mindfulness practice is safe and effective. It shifts us from our future thoughts and worries,  drawing us towards our present moment awareness.  It invites us to notice what is there, to hear the whole of ourselves, and if this self is loudly saying "I don't like this," then we owe it to ourselves to take notice of this voice.
Tips for staying safe:

Take account of your personal history 
If you have a past history of trauma, panic attacks, or PTSD, consider carefully whether the practices may re-trigger something for you. You may want to consider limiting the length of your practice, discussing your needs with your teacher, and avoiding some forms of mindful practice.

During practice 
If you start to feel uncomfortable,  particularly if you feel rising anxiety, do not assume your feeling is a barrier to break through, because this is likely to make things worse. Stop your practiceOpen your eyes, and look around the room. Move your body, shake, fidget, rub your skin, get up and walk around. Say to yourself "I am OK, this feeling will pass, I am safe now." Let your teacher know. 

After practice 
If you have a strong feeling of panic or anxiety, it may leave you feeling strange for a considerable period afterwards. You may have feelings of disorientation, being in a fog, unreality, your body feeling distorted, or a sense of floating. You may also have these kinds of feelings after a pleasant mindful experience. Take extra care, especially if you are considering driving or performing complex tasks. 

Seek help 
If the strange feelings do not subside, or you experience further troubling episodes of anxiety or intrusive thoughts or images, let one of the facilitators know.